Experts in capsule blinding methodologies
Over-encapsulation is a blinding methodology that involves hiding a tablet or capsule inside an opaque capsule shell (often involving the addition of a backfilled excipient to prevent rattling), so that the contents are concealed, creating products that are visually identical.
At Eramol, we are skilled in over-encapsulation and can offer over-encapsulation of tablets or capsules. Our expertise in this area includes:
- Existing placebo capsule formulations with enhanced stability data
- Choice from a wide range of capsule shells and sizes
- Automated and semi-automated capsule filling equipment
- Over-encapsulation of multiple tablets or capsules into single capsule shells
Active Capsule manufacture
Experts in neat-fill API capsule
Neat-filling of API into capsule shells provides rapid manufacturing options for early phase clinical trial drug products.
Eramol has completed a number of neat-fill API capsule manufacturing campaigns for early phase studies in the UK and EU. Manual and semi-automated capsule filling processes are well established to cater for small scale batch production and where material reconciliation is critical.