Over-Encapsulation

Over-Encapsulation

Experts in capsule blinding methodologies

Over-encapsulation is a blinding methodology that involves hiding a tablet or capsule inside an opaque capsule shell (often involving the addition of a backfilled excipient to prevent rattling), so that the contents are concealed, creating products that are visually identical.

At Eramol, we are skilled in over-encapsulation and can offer over-encapsulation of tablets or capsules. Our expertise in this area includes:

  • Existing placebo capsule formulations with enhanced stability data
  • Choice from a wide range of capsule shells and sizes
  • Automated and semi-automated capsule filling equipment
  • Over-encapsulation of multiple tablets or capsules into single capsule shells

Active Capsule manufacture

Experts in neat-fill API capsule

Neat-filling of API into capsule shells provides rapid manufacturing options for early phase clinical trial drug products.

Eramol has completed a number of neat-fill API capsule manufacturing campaigns for early phase studies in the UK and EU.  Manual and semi-automated capsule filling processes are well established to cater for small scale batch production and where material reconciliation is critical.

Eramol has completed a number of neat-fill API capsule manufacturing campaigns for early phase studies in the UK and EU.  Manual and semi-automated capsule filling processes are well established to cater for small scale batch production and where material reconciliation is critical.

Neat-filling of API into capsule shells provides rapid manufacturing options for early phase clinical trial drug products.

Our Other Services

Sterile Manufacturing

Eramol delivers a purpose-built, EU GMP Annex 1–compliant sterile manufacturing service dedicated to Phase I and Phase II clinical trial supply. Our facility is designed for agility, reliability, and regulatory strength by integrating advanced isolator technology, closed-system processing, moist heat terminal sterilisation and a full end-to-end clinical supply chain — ensuring your sterile injectable, cartridges and pre filled syringes reach patients safely, on time and in full regulatory compliance.

Non Sterile Manufacturing

GMP Production of Tablets, Capsules & Oral Liquids for Phase I–III and Commercial Supply Eramol delivers end-to-end non-sterile manufacturing built on a foundation of quality, regulatory expertise, and Qualified Person (QP) leadership. Our Sevenoaks GMP facility, commissioned in November 2021 and operational since August 2022, supports the full product lifecycle—from early-phase clinical development right through to commercial supply.

Labelling Solutions

Our versatile and extensive labelling solutions have been designed to offer flexibility, economy of scale and to meet the demands of last-minute requirements.

Reliable. Proven. Safe. Effective.

Reliable. Proven. Safe. Effective.

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